The COPE Consortium operated from January 2013 to June 2018, thanks to funding through the EU's 7th Framework Programme on research, technological development and demonstration. The Consortium served as the official organ preservation task force of the European Society for Organ Transplantation (ESOT). COPE assembled academic institutions, clinical and scientific experts and small and medium sized enterprises from across Europe to work together on advancing organ preservation techniques.

The COPE Consortium advanced and developed organ preservation technologies by performing clinical and translational studies with on-going experimental refinement. Through testing quality and safety, increasing the efficiency and refining preservation strategies we set out to bring technologies from the bench to the bedside.

Focusing on three clinical trials and two experimental work programmes across Europe, COPE worked to improve preservation and reconditioning strategies for kidneys and livers procured for transplantation. By exploiting collaborations between industry and academic institutions we have introduced organ preservation technologies that will increase the number and quality of grafts used for transplantation.

COPE has formally concluded with the end of the grant, but follow-up work continues. Trial results, health economic analyses, experimental results, and bio-repository study outcomes continue to be completed and released.

Links & Resources

NHS Blood and Transplant is the British body governing transplantation in the UK.

Eurotransplant is a non-profit organisation that facilitates patient-oriented allocation and cross-border exchange of deceased donor organs on the European continent.

The European Commission's Directorate for Research and Innovation funds research projects such as COPE.

ESOT - European Society for Organ Transplantation - has a wealth of information for patients and professionals.

COMPARE trial: new hope for organ preservation. The results of the kidney perfusion trial (WP4) are now available in The Lancet.

Abstracts presenting the results of the COMPARE trial have been accepted for presentation at the 2019 Belgian Transplant Congress (4 March; awarded Best Abstract), the Dutch Bootcongress and the 2019 American Transplant Congress (1-5 June).

Our POMP trial has reached its recruitment target! Recruitment was completed on 18 May 2018 with a total of 262 kidneys, the last of which was recruited in Budapest.  

The outcome of the liver perfusion trial (WP2) was featured on the cover of Nature in April 2018, and received additional media coverage on the BBC and elsewhere.

Organ preservation techniques were featured on the BBC 4 radio programme "Inside Health"! Listen to Professor Ploeg and David Nasralla by clicking here.

This project has received funding from the European Union's 7th Framework Programme for research, technological development and demonstration under grant agreement 305934.

COPE Consortium - 2018